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A real-world cohort study looked at the risks of developing ICIP in NSCLC patients who received prior radiotherapy and are currently on ICI therapy

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Tirzepatide, but not semaglutide, was capable of reducing aspartate aminotransferase (AST), alanine aminotransferase (ALT) and liver stiffness levels, and it was associated with a significantly higher rate of metabolic dysfunction-associated steatohepatitis (MASH) remission and a decrease of at least one stage of liver fibrosis

It says patients with robust B12 stores may simply not need the addition